In a bowl, blend together the flour, 2 tablespoons of sugar, baking powder, baking soda, and salt.
With a pastry blender, cut in the butter until coarse crumb-like mixture forms.
In another bowl, add egg and beat well.
Transfer 2 tablespoons of beaten egg into another small bowl. Set aside.
In the bowl of the remaining egg, add buttermilk and vanilla extract and beat until well combined.
Add the flour mixture and mix until just combined.
Gently fold in the blueberries.
Place the dough into a lightly floured surface.
With your hands, gently knead until a non-sticky dough forms.
Then with your hands, pat down the dough into a 6-inch circle.
Cut the dough circle into 8 equal-sized wedges.
Grease the Air Fryer Basket with cooking spray and then slide inside.
Adjust the temperature of Air Fryer to 360 °F to preheat for 5 minutes.
After preheating, arrange the dough wedges into the greased Air Fryer Basket in a single layer.
Slide the basket into Air Fryer and set the time for 6 minutes.
After cooking time is finished, remove the scones from Air Fryer and serve warm.